DEA Form 251 Instructions for Registrant Certificate
This file provides important instructions for completing the DEA Form 251, CSOS DEA Registrant Certificate Application. It is essential for DEA Registrants seeking to obtain a CSOS digital certificate for ordering controlled substances. Ensure to follow all steps to avoid delays in the application process.
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How do I fill this out?
To fill out the DEA Form 251, applicants must provide all required personal and registration information accurately. Ensure to complete the necessary signatures in blue or black ink. Review the application checklist thoroughly before submitting your application.

How to fill out the DEA Form 251 Instructions for Registrant Certificate?
1
Visit the DEA website and access the DEA Form 251.
2
Fill out all required fields with accurate information.
3
Sign the application in blue or black ink as required.
4
Review the CSOS Application Checklist to ensure completeness.
5
Mail the completed application to the DEA at the provided address.
Who needs the DEA Form 251 Instructions for Registrant Certificate?
1
DEA Registrants who want to order controlled substances electronically.
2
Pharmacies needing to ensure compliance with CSOS regulations.
3
Healthcare organizations that require digital certificate access.
4
Authorized individuals acting as Power of Attorney for a DEA Registrant.
5
Coordinators managing CSOS certificate applications.
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What are the instructions for submitting this form?
To submit the DEA Form 251, complete all required fields and include necessary supporting documents. Mail the application package to the DEA at: Drug Enforcement Administration, Sterling Park Technology Center / CSOS, 8701 Morrissette Drive, Springfield, VA 22152. For assistance, please contact DEA Diversion E-Commerce Support at 1-877-DEA-ECOM (1-877-332-3266) or via email at CSOSsupport@deaecom.gov.
What are the important dates for this form in 2024 and 2025?
No specific important dates are mentioned; however, ensure timely submissions to avoid processing delays.

What is the purpose of this form?
The purpose of DEA Form 251 is to facilitate DEA Registrants in obtaining a CSOS digital certificate for electronic orders. This process is crucial for keeping controlled substance ordering compliant and efficient. Successful completion of this form ensures a smoother application process with the DEA.

Tell me about this form and its components and fields line-by-line.

- 1. Applicant Last Name: Registrant applicant's last name.
- 2. Applicant First Name: Registrant applicant's first name.
- 3. Applicant Social Security Number: Social Security Number for authentication.
- 4. Applicant Business Phone: Business contact number.
- 5. Applicant E-mail Address: Unique email address for correspondence.
- 6. DEA Registration No.: DEA Registration Number being requested.
- 7. DEA Registrant Name: Name of registered DEA location.
- 8. Security Code: Code used for application authentication.
- 9. No. of Addendums: Number of additional addendums submitted.
- 10. Applicant Business Address: Business address of the applicant.
- 11. CSOS Coordinator Last Name: Last name of the CSOS Coordinator.
- 12. CSOS Coordinator First Name: First name of the CSOS Coordinator.
What happens if I fail to submit this form?
Failure to submit this form can result in delays in obtaining the necessary CSOS digital certificates. Without proper submission, DEA Registrants may face challenges in ordering controlled substances electronically. It is crucial to address any issues promptly to avoid operational disruptions.
- Delayed Processing: Missing information can lead to a longer application review time.
- Application Denial: Incomplete forms may be rejected, requiring resubmission.
- Compliance Issues: Failure to comply with registration could lead to legal impacts.
How do I know when to use this form?

- 1. Electronic Ordering Needs: To apply for the ability to order controlled substances electronically.
- 2. CSOS Coordinator Application: For individuals applying as a CSOS Coordinator.
- 3. Power of Attorney Role: When acting on behalf of another DEA Registrant.
Frequently Asked Questions
What is DEA Form 251?
DEA Form 251 is used by DEA Registrants to apply for a CSOS digital certificate for ordering controlled substances.
How do I fill out the DEA Form 251?
Fill out all required fields, sign in blue or black ink, and review the application checklist before submission.
Who needs this form?
DEA Registrants, authorized individuals, pharmacies, and healthcare organizations must complete this form to access CSOS.
How can I edit the PDF on PrintFriendly?
You can easily edit the PDF by selecting the text and making modifications directly within the document.
Is a digital signature accepted?
Yes, you can use our signature tools to add your electronic signature securely.
What documents should accompany the application?
Applicants must include all necessary attachments as outlined in the CSOS application checklist.
How do I submit the completed form?
Submit your completed DEA Form 251 and attachments via mail to the DEA provided address.
Can I download the edited file?
Yes, after editing you can download the final version of your PDF for your records.
What if I make a mistake on the form?
Review your form carefully before submission; mistakes can lead to delays.
Where can I find the DEA contact information?
The DEA's contact information for support is included on their official website.
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