Form-224 Application for Registration under Act
This form is essential for individuals and businesses applying for registration under the Controlled Substances Act. It addresses various aspects of the registration process and provides important details on applicant identification and liability. Completing this form is crucial to comply with DEA regulations.
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How do I fill this out?
Filling out this application requires careful attention to detail. Start by entering your identification information accurately in Section 1. Complete each section methodically, ensuring all necessary information is provided.

How to fill out the Form-224 Application for Registration under Act?
1
Read the instructions carefully before filling out the form.
2
Fill in all required sections including applicant identification and business activities.
3
Check the appropriate boxes for drug schedules you are applying for.
4
Provide accurate contact information for the applicant and business.
5
Review the completed form for accuracy before submission.
Who needs the Form-224 Application for Registration under Act?
1
Pharmacies need this form to register to handle controlled substances.
2
Healthcare practitioners require this form to prescribe medications legally.
3
Veterinary clinics must complete this form to manage narcotics safely.
4
Research institutions need this form to conduct studies involving controlled substances.
5
Government entities require this form for compliance in handling drugs.
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What are the instructions for submitting this form?
To submit Form-224, you can apply online through the DEA's official website or mail a completed copy of the application to the DEA Headquarters, registration section. The mailing address for submission is: DEA Headquarters, ATTN: Registration Section/ODR, P.O. Box 2639, Springfield, VA 22152-2639. Professional healthcare practitioners can contact the DEA at 800-882-9539 for additional inquiries before submitting their application.
What are the important dates for this form in 2024 and 2025?
The current version of Form-224 expires on January 31, 2016, but regular updates from the DEA are essential for future compliance. Keep an eye out for any future announcements regarding updated forms in 2024 and 2025.

What is the purpose of this form?
The purpose of Form-224 is to provide a standardized application process for individuals and entities seeking registration under the Controlled Substances Act. It ensures that prospective registrants are thoroughly vetted before they are permitted to handle controlled substances. This helps the DEA regulate and monitor the distribution of drugs appropriately.

Tell me about this form and its components and fields line-by-line.

- 1. Applicant Identification: Identifying information of the individual or business applying.
- 2. Business Activity: Details regarding the type of business activity the applicant engages in.
- 3. Drug Schedules: Specifies which drug schedules the applicant intends to handle.
- 4. State License(s): Information about state licenses relevant to controlled substances.
- 5. Liability: Questions related to any past criminal activity or license revocations.
- 6. Exemption from Application Fee: Indicates if the applicant is exempt from paying the fee.
- 7. Method of Payment: Indicates how the application fee will be paid.
- 8. Applicant's Signature: Section for the applicant to sign and certify the information provided.
What happens if I fail to submit this form?
Failing to submit Form-224 can lead to serious consequences. Applicants could face legal actions for handling controlled substances without the necessary registration. Additionally, it could result in delays in obtaining drugs for legitimate medical or business purposes.
- Legal Repercussions: Handling controlled substances without proper registration may lead to fines or imprisonment.
- Operational Delays: Without the necessary registration, businesses may face interruptions in their services.
- Regulatory Scrutiny: Failure to comply with submission requirements may lead to scrutiny from regulatory agencies.
How do I know when to use this form?

- 1. Pharmacies: For the legal distribution of prescriptions containing controlled substances.
- 2. Healthcare Providers: To prescribe medications that fall under controlled substances.
- 3. Veterinary Practices: For the administration of controlled substances to animals.
- 4. Research Institutions: For conducting studies that involve controlled drugs.
- 5. Educational Institutions: When teaching programs require handling narcotics for educational purposes.
Frequently Asked Questions
What is Form-224?
Form-224 is an application for registration under the Controlled Substances Act, enabling individuals and businesses to handle controlled substances legally.
How do I submit Form-224?
You can submit Form-224 online through the DEA's website, or by mailing it to the specified DEA address.
Who needs to fill out Form-224?
Anyone or any entity that intends to handle controlled substances must complete this form.
Can I edit Form-224 on PrintFriendly?
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What if I make a mistake on the form?
If there are mistakes, you can edit the PDF again before downloading the final version.
Is there a fee associated with this application?
Yes, there is a non-refundable fee of $731 for processing the application.
How can I sign the form?
You can add your signature in the PrintFriendly editor by using the signing tools provided.
What happens if I don’t submit this form?
Failing to submit this form can lead to legal implications regarding the handling of controlled substances.
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